Wheat: 200 Clinically Confirmed Reasons Not To Eat It

With sales of foods labeled gluten free now reaching over 6 billion dollars a year, something truly profound is happening to the way in which Americans are perceiving the role of wheat in their diets. Once celebrated as the very poster-child of the health food movement, folks are increasingly rejecting this “king of grains,” and are now identifying it as being at the very root of their health problems.

Detractors claim that the movement is just a fad, or worse, that those who have embarked upon it without an official diagnosis are a bit crazy. After all, simply “feeling better” following gluten elimination is not considered to be proof of anything within the conventional medical system.  Biopsies, antibody, and genetic tests later, if nothing is found, and you still think gluten – this ‘sacred,’ omnipresent grain – is a problem, you might just get referred to a psychiatrist.

But anecdotes and “subjective experience” aside, the type of clinical research that constitutes “Truth,” with a capital T, from the perspective of the dominant medical establishment, can be found on the National Library of Medicine’s biomedical database known as MEDLINE. This vast bibliographic archive contains over 21 million citation entries, which as of time of this writing, contains 9,776 references to gluten.

There has been a sharp increase in interest and research on the topic of “gluten intolerance” – although we prefer to label the subject “gluten toxicity,” in order to shift the focus away from the “victim” back to the “aggressor,” the gluten itself. In 1971, there were 71 studies listed on MEDLINE which referenced gluten. Last year in 2011, there were 514.

At present, the conventional medical establishment only identifies a handful of disorders likely to be caused by wheat consumption, such as:

  • Wheat Allergy
  • Celiac Disease
  • Dermatitis Herpetiformis
  • Exercise-Induced Wheat Anaphylaxis

These conditions, however, are but the tip of a massive “celiac” iceberg.  In a previous essay, The Dark Side of Wheat, we discussed the problem from a more philosophical perspective.  There is now, however, a huge dataset firmly establishing the likelihood that wheat intolerance, or better yet, wheat toxicity, is a universal, human species-specific problem, occurring only in differing degrees, and mostly sub-clinically, at least through the optic of conventional screenings and technologies.

One must also account for the “invisible thorn,” which is wheat lectin – known more technically as Wheat Germ Agglutinin (WGA) — and which can cause a broad range of adverse health effects, even while being undetected through conventional screenings.  Learn more about this topic in our essay Opening Pandora’s Bread Box: The Critical Role of Wheat Lectin in Human Disease.

In order to fully appreciate the extent of damage wheat and/or gluten consumption can have on the body, included “sprouted wheat” (since WGA is still present), view the screenshot from Green Med Info Wheat page below:

Name Cumulative Knowledge Article Count Focus Articles
Celiac Disease 1395 150
Wheat Intolerance 402 29
Gluten Sensitivity 380 35
Gluten Intolerance 336 27
Autoimmune Diseases 136 12
Schizophrenia 111 7
Food Allergies: Wheat 106 11
Food Allergies 97 10
Psoriasis 82 5
Down Syndrome 80 5
Diabetes Mellitus: Type 1 73 12
Irritable Bowel Syndrome 71 4
Diabetes Mellitus: Type 1: Prevention 70 8
Celiac Disease: Diagnostic Considerations 63 7
Autism Spectrum Disorders 61 5
Sjogren’s Syndrome 60 3
Cerebellar Ataxia 53 4
Dermatitis Herpetiformis 50 4
Epilepsy 50 6
Graves Disease 50 3
Liver Disease 50 2
Multiple Myeloma 50 3
Multiple Sclerosis 50 3
Migraine Disorders 44 5
Atopic Dermatitis 40 4
Casein Intolerance 40 2
Gastroesophageal Reflux 40 2
Hyperthyroidism 40 2
Anaphylaxis: Exercise-Induced 37 5
IgA Nephropathy 36 3
Gastrointestinal Inflammation 34 5
Infertility 31 2
Autoimmune Thyroiditis 30 2
Cirrhosis: Liver 30 1
Diarrhea: IBS associated 30 1
Hypothyroidism 30 3
IgA rheumatoid factor: elevated 30 2
Infertility: Female 30 1
Non-Hodgkin Lymphoma 30 3
Polyarthritis 30 1
Psychoses 30 1
Eosinophilic esophagitis 26 4
Epilepsy: With Cerebral Calcifications 25 3
Cerebral Calcifications 23 2
Diarrhea 23 3
Celiac Disease: Prevention 22 2
Abortion: Spontaneous 21 2
Ataxia: Cerebellar 21 3
Miscarriage: Recurrent 21 2
Thyroid Nodule 21 2
Atherosclerosis 20 1
Attention Deficit Disorder with Hyperactivity 20 2
Attention Deficit Hyperactivity Disorder 20 1
Autism 20 1
Cardiomyopathy 20 1
Cholestasis 20 1
Cholestasis: Autoimmune 20 1
Coronary Artery Disease 20 1
End-Stage Autoimmune Liver Disease (ESALD) 20 1
Hashimoto’s thyroiditis 20 1
IgE-Mediated Hypersensitivity 20 2
Infant Nutrition 20 1
Meniere’s Disease 20 1
Organ Transplantation: Liver 20 1
Palmoplantar Pustulosis 20 1
Peripheral Neuropathies 20 1
Restless Legs Syndrome 20 2
Rett Syndrome 20 1
Sensory Neuropathies 20 1
Macroamylasemia 19 4
Intestinal Permeability 17 6
Asthma 15 4
Ataxia 14 3
Headache 13 2
Pancreatitis 13 2
Lymphoma 12 2
Psychiatric Disorders 12 2
Cancers: All 11 2
Rheumatoid Arthritis 11 2
Thyroid Cancer 11 2
Acquired hypogammaglobulinemia 10 1
Allergy: Cow’s Milk 10 1
Anaphylaxis 10 1
Aphthous Ulcer 10 1
Ataxia: Dominant 10 1
Ataxia: Sporadic 10 1
Atopic Dermatitis: Infant & Childhood 10 1
Attention Deficit Disorder 10 1
Brain Injury: Hippocampal Damage 10 1
CNS White Matter Abnormalities 10 1
Carpal Tunnel Syndrome 10 1
Celiac Disease: Early Onset 10 1
Child Mortality 10 1
Children: Impaired Growth 10 1
Chronic Constipation, Children 10 1
Colitis: Collagenous 10 1
Constipation 10 1
Depression: Unipolar 10 1
Diarrhea: in Children 10 1
Enamel Defects 10 1
Epithelium Damage: Lymphocytic infiltration 10 1
Food Allergies/Intolerances: Cereals/Grains 10 1
Gastrointestinal Hemorrhage 10 1
Gluten Ataxia 10 1
Hepatitis: Autoimmune 10 1
Hippocampal Sclerosis 10 1
Hypertransaminasemia 10 1
Hypogammaglobulinemia 10 1
Kidney Cancer 10 1
Liver Fibrosis 10 1
Mania: Acute 10 1
Microscopic Colitis Syndrome 10 1
Mortality: All-Cause 10 1
Mucosa: Flattened 10 1
Myocarditis: Autoimmune 10 1
Myopathies 10 1
Myopathies: Inflammatory 10 1
Nervous System Diseases 10 1
Neurological Illness: GAD antibody-associated 10 1
Nightshade Foods Intolerance 10 1
Pregnancy: Prevention of Problems 10 1
Small-for-gestational-age infant 10 1
Spinocerebellar Ataxia Type 2 10 1
Stiff-Person Syndrome 10 1
Stomatitis: Aphthous 10 1
Temporal Lobe Epilepsy (TLE) 10 1
Thyroid Neoplasms 10 1
Turner Syndrome 10 1
Urinary Stone Disease 10 1
Kidney Diseases 9 2
Prolactin: Inappropriate Secretion 8 2
Anemia 7 2
Conjunctival Tumor 6 1
Ectopic Calcification 6 1
Encephalopathies 6 1
Glomerulonephritis 6 1
Hypocalcemia 6 1
Neuromyelitis Optica 6 2
Pituitary Diseases 6 1
Polyneuropathies 6 1
Prolactin Hypersecretion Syndrome 6 2
Seizures 6 1
Splenic Calcifications 6 1
Splenic Diseases 6 1
Systemic Lupus Erythematosus 6 1
Urticaria 6 2
Immune Disorders: Low Immune Function 5 1
Malabsorption Syndrome 5 2
Enteropathy 4 2
Insulin: Elevated 4 2
Male Hormone Imbalances 4 1
Diabetes Mellitus: Type 2 3 1
Facial Palsy 3 1
Folic Acid/Folate Deficiency 3 1
Food Allergy: Immunoglobulin E-mediated 3 1
Gastrointestinal Diseases 3 2
Hydronephrosis 3 1
Hyperamylasemia 3 1
Inflammation 3 2
Insulin Disorders 3 2
Kidney Stones 3 1
Opiate Addiction/Withdrawal 3 1
Osteogenesis Imperfecta 3 1
Osteomalacia 3 1
Osteopenia 3 1
Osteoporosis 3 1
Parathyroid Diseases 3 1
Parathyroid adenoma 3 1
Stroke 3 1
Thrombosis 3 1
Tremor 3 1
Urolithiasis 3 1
Uveitis 3 1
A1C 2 1
Allergies 2 1
Blood-Brain-Barrier Disorders 2 2
Demyelinating Diseases 2 1
Diabetes: Glycation/A1C 2 1
Drug Toxicity: Methotrexate 2 1
Glucagon: Excess Secretion 2 1
Gynecomastia 2 1
HPA Axis Dysregulation 2 1
Insulinitis 2 1
Low Immune Function: Thymus Dysfunction 2 1
Serotonin Disorders 2 1
Thymus Atrophy 2 1
Ataxia: Idiopathic 1 1
Brain: Microglial Activation 1 1
Breast Cancer 1 1
Chorea 1 1
Clotting 1 1
Dementia 1 1
Food Poisoning 1 1
Guillain-Barre Syndrome 1 1
Huntington Disease 1 1
Hyperinsulinism 1 1
Insulin Resistance 1 1
Lane-Hamilton syndrome 1 1
Lectin-Induced Toxicity 1 1
Miscarriage 1 1
Myelopathy 1 1
Neurologic Disorders 1 1
Neuropathy 1 1
Osteoarthritis 1 1
Oxidative Stress 1 1
Quick Summary: 20 associated Adverse Pharmacological Actions
Name Cumulative Knowledge Article Count Focus Articles
Neurotoxic 287 23
Immunoreactive 128 13
Immunotoxic 99 9
Teratogenic 91 4
Inflammatory 40 6
Interleukin-15 downregulation 22 2
Proliferative 20 1
Nephrotoxic 13 2
Diabetogenic 12 4
Allergenic 11 2
Cardiotoxic 10 1
Endocrine Disruptor 6 2
Immunosuppressive 5 1
Cytotoxic 4 4
Endocrine Disruptor: Insulin Resistance 2 1
Endocrine Disruptor: Pancreas 2 1
Serotonin Down-Regulation 2 1
Interleukin-4 Up-Regulation 1 1
Oxidant 1 1
Vascular Endothelial Growth Factor C Up-Regulation 1 1


From Around the Web